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Photosensitizers/Nutrient Depletion:- BiotinBiotin: Based on human evidence, isotretinoin (Accutane®) may reduce biotinidase activity (10325581).
- CarnitineCarnitine: Human evidence indicates that isotretinion therapy may decrease L-carnitine (L-car) blood levels in patients with cystic acne (10642057). L-car supplementation might treat liver and muscular side effects of the drug. Another human study, however, indicated that isotretinion therapy had no effect on carnitine levels (2958078).
- LycopeneLycopene: In clinical study, consumption of tomato paste containing lycopene with pasta and olive oil was associated with increased serum lycopene levels and a 40% reduction in skin erythema caused by ultraviolet (UV) light, when compared to controls (11340098). In another clinical study, skin levels of lycopene were decreased after exposure to UV light (7616301).
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Copyright © 2011 Natural Standard (www.naturalstandard.com)
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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.
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